The political support for investing in women’s economic empowerment (WEE) has never been higher. Especially in light of the disparate impacts from COVID-19 on women and girls, there has been a loud chorus of voices on the need to invest in WEE. The critical question, though, is whether the political rhetoric is matched by effective, catalytic investments that are significantly advancing women and girls’ equality and giving them the meaningful ability to participate in, and benefit from, economic opportunities and prosperity?